COVID-19 has become a global threat, endangering not only the health and welfare but also the peaceful coexistence and social cohesion of our communities. This guide provides practical examples and recommendations that spur the growth of existing interfaith initiatives, and the establishment of new ones, to address some of the many challenges related to COVID-19, while emphasising the development and strengthening of cross-community relations through dialogue. It also highlights ways in which interreligious dialogue strengthens initiatives that foster joint open communication and diversity to prevent further community disconnection, isolation, wastage of resources and deeper distrust.